signalingpathways相关论文
大面积深度烧伤患者因汗腺毁损导致体温调节功能基本丧失,生活质量受到严重影响。目前对于修复汗腺功能的研究较多,然而人体汗腺发育......
Ischemic stroke is a leading cause of morbidity and mortality worldwide.Resident microglia are the principal immune cell......
The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflato
Aflatoxin B1(AFB1)is a potent immunosuppressive agent in endotherms,which can be related to the up-regulated apoptosis o......
The crustaceans are one of the largest and most diverse group of invertebrates,which evolved through a complex polymorph......
HSP70 induces cytokine expression and release via MAPK and/or NF-κB pathways in grass carp head kidn
Cytokine function of heat shock protein 70(HSP70)has been well documented in mammals....
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Human amniotic epithelial stem cells promote wound healing by facilitating the migration and prolife
Wound healing is a highly orchestrated physiological process consisting of a complex interaction of cellular and biochem......
Visfatin as a Potential Biomarker stimulates endometrial cancer cell proliferation via activation of
Objective: Visfatin,a newly discovered adipocytokine,is thought to play a role in pathogenesis of metabolic-syndrome-rel......
The potential utility of acetyltanshinone Ⅱ A in the treatment of HER-2-overexpressed breast cancer:
Aim HER-2 is an important oncoprotein which overexpression, found in more than 30% of breast cancers, is strongly associ......
Multi-target drugs, such as cocktail therapy used for treating AIDS, usually show strong efficacy than single-target dru......
As a transcription factor, c-Myc exerts significant influence in cancer development through regulating a large number of......
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Febuxostat, a nonpurine selective inhibitor of xanthine oxidase: a promising medical therapy for chr
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血-睾屏障由相邻支持细胞间多种蛋白质复合体组成,它通过在生精上皮参与构建生精微环境、提供免疫屏障并赋予细胞极性来维持正常精......
Co-operative Regulation of N-glycan Structures and Phosphorylation of Proteins in Cold and Salt Stre
N-glycosylation impacts on the structure,conformation and stability of glycoproteins,and functions in regulating pla......
Wnt和MAPK信号通路在生物进化过程中高度保守,参与调控胚胎发育和细胞增殖、分化及凋亡等。Wnt和MAPK信号通路调控失常可导致胚胎发......
糖尿病肾病( DN)是糖尿病的主要并发症之一,也是引起终末期肾病和糖尿病患者死亡的常见原因。多种机制参与DN的发生、发展,如糖、脂......
促酰化蛋白(ASP)是脂肪组织分泌的一种生物活性物质,ASP与细胞表面的特异性受体结合,在人C5 a新型受体、蛋白激酶C和磷脂酰肌醇3-激酶等......
支气管哮喘(哮喘)是临床常见的慢性气道炎症性疾病,多种细胞及其组分参与哮喘发病。肺组织巨噬细胞是呼吸道中重要的免疫细胞,在不同疾......
骨髓间充质干细胞(BMSCs)具有自我更新和多向分化能力,并有归巢损伤处修复组织等功能,在组织工程修复与再生医学中有广泛的应用.近......
近年来,恶性肿瘤的发病率逐渐增加,对于恶性肿瘤的发病及转移机制的研究也越来越深入。研究发现,肿瘤的发病及转移可能与上皮间质转化......
Ursolic acid (UA) is a pentacyclic triterpene of the ursane type.As a common chemical constituent among species of the f......
Dietary isoflavones, the modulator of breast carcinogenesis: Current landscape and future perspectiv
Breast cancer is a frightful disease and serious conc in women around the world causing significant health care burden i......
Mammalian cells have the ability to respond to a myriad of diverse extracellular stimuli that modulate cell function. Th......